Malignant Transformation of Ovarian Epithelium

Stroma by, Malignant Human Breast Cancer Epithelium Spontaneous Fusion with, and Transformation of Mouse

Adenocarcinoma cells from the pleural effusion of a patient with breast cancer were injected into the mammary glands of nude mice and grown into solid tumors. A cell line derived from these tumors expressed A-smooth muscle actin but not human cytokeratin 7, indicating ‘‘activated’’ stroma of mouse origin. Cells in mitosis exhibited mainly polyploid mouse karyotypes, but 30% had mixed mouse and ...

Malignant Transformation of both Ectopic Glandular Epithelium and Stroma Arising from Different Endometriotic Sites: Case Report

Malignant transformation of osteoblastoma.

A recurrent spinal tumor confidently diagnosed as osteoblastoma eventually terminated as a sclerosing osteoblastic which metastasised nine years after the onset of symptoms.

Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium.

Adenocarcinoma cells from the pleural effusion of a patient with breast cancer were injected into the mammary glands of nude mice and grown into solid tumors. A cell line derived from these tumors expressed alpha-smooth muscle actin but not human cytokeratin 7, indicating "activated" stroma of mouse origin. Cells in mitosis exhibited mainly polyploid mouse karyotypes, but 30% had mixed mouse an...

Cell surface changes associated with malignant transformation of bladder epithelium in vitro.

Three properties of cell surface membranes of normal bladder epithelium and of two malignant urothelial lines transformed in vitro by Dr. Y. Hashimoto and Dr. H. S. Kitagawa were analyzed by means of morphological and chemical tools. Under scan electron microscopy, normal bladder epithelium displayed an appearance devoid of the pleomorphic, abundantly distributed, microvillous structures seen o...